Target：UBAP1

Gene Name：UBAP1 NAG20

Protein Name：Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)

Human Gene Id：51271

Human Swiss Prot No：Q9NZ09

Mouse Swiss Prot No：Q8BH48

Rat Swiss Prot No：Q5XIS7

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：UBAP1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：55kD

Background： This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

Function：similarity:Contains 2 UBA domains.,tissue specificity:Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.,

Subcellular Location：Cytoplasm, cytosol . Endosome . Predominantly cytosolic (PubMed:21757351). Recruited to endosomes as part of the ESCRT-I complex (PubMed:21757351). .

Expression：Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.