Target：VIP

Fields：cAMP signaling pathway;Neuroactive ligand-receptor interaction

Gene Name：VIP

Protein Name：VIP peptides

Human Gene Id：7432

Human Swiss Prot No：P01282

Mouse Swiss Prot No：P32648

Immunogen：The antiserum was produced against synthesized peptide derived from human VIP. AA range:71-120

Specificity：VIP Polyclonal Antibody detects endogenous levels of VIP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：VIP;VIP peptides

Observed Band(KD)：20kD

Background： The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014],

Function：function:PHM and PHV also cause vasodilation.,function:VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.,online information:Vasoactive intestinal peptide entry,similarity:Belongs to the glucagon family.,

Subcellular Location：Secreted.

Expression： Pancreatic carcinoma,Pheochromocytoma,Prostate,