Target：Z280B

Gene Name：ZNF280B SUHW2 ZNF279 ZNF632

Protein Name：Zinc finger protein 280B (5'OY11.1) (Suppressor of hairy wing homolog 2) (Zinc finger protein 279) (Zinc finger protein 632)

Human Gene Id：140883

Human Swiss Prot No：Q86YH2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：Z280B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：59kD

Background： The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015],

Function：function:May function as a transcription factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 4 C2H2-type zinc fingers.,

Subcellular Location：Nucleus .

Expression： Testis,Uterus,