Target：TRP14
Gene Name：TXNDC17
Protein Name：Thioredoxin domain-containing protein 17
Human Gene Id：84817
Human Swiss Prot No：Q9BRA2
Mouse Gene Id：52700
Mouse Swiss Prot No：Q9CQM5
Immunogen：Synthesized peptide derived from TRP14 . at AA range: 20-100
Specificity：TRP14 Polyclonal Antibody detects endogenous levels of TRP14 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：TXNDC17;TXNL5;Thioredoxin domain-containing protein 17;14 kDa thioredoxin-related protein;TRP14;Protein 42-9-9;Thioredoxin-like protein 5
Observed Band(KD)：13kD
Background：function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines.,
Function：function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines.,
Subcellular Location：Cytoplasm .
Expression：Ubiquitously expressed in cell lines.
