Target:Troponin I-C
Gene Name:TNNI3
Protein Name:Troponin I cardiac muscle
Human Swiss Prot No:P19429
Mouse Gene Id:21954
Rat Gene Id:29248
Rat Swiss Prot No:P23693
Immunogen:The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54
Specificity:Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TNNI3;TNNC1;Troponin I; cardiac muscle;Cardiac troponin I
Observed Band(KD):28kD
Background:Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).