Target：TRI35

Gene Name：TRIM35 HLS5 KIAA1098

Protein Name：Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5)

Human Gene Id：23087

Human Swiss Prot No：Q9UPQ4

Mouse Swiss Prot No：Q8C006

Rat Swiss Prot No：Q5RKG6

Immunogen：Synthesized peptide derived from human protein . at AA range: 320-400

Specificity：TRI35 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：54kD

Background： The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008],

Function：domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.,

Subcellular Location：Cytoplasm . Nucleus . Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity). .

Expression： Brain,Liver,Lung,