Target：ZNF384

Gene Name：ZNF384

Protein Name：Zinc finger protein 384

Human Gene Id：171017

Human Swiss Prot No：Q8TF68

Rat Gene Id：171018

Rat Swiss Prot No：Q9EQJ4

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50

Specificity：ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZNF384;CAGH1;CIZ;NMP4;TNRC1;Zinc finger protein 384;CAG repeat protein 1;CAS-interacting zinc finger protein;Nuclear matrix transcription factor 4;Nuclear matrix protein 4;Trinucleotide repeat-containing gene 1 protein

Observed Band(KD)：64kD

Background：zinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011],

Function：alternative products:Additional isoforms seem to exist,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 8 C2H2-type zinc fingers.,subunit:Interacts with BCAR1.,

Subcellular Location：Nucleus .

Expression： Brain,Brain cortex,Testis,