Target:ZN335
Gene Name:ZNF335
Protein Name:Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1)
Human Gene Id:63925
Human Swiss Prot No:Q9H4Z2
Mouse Swiss Prot No:A2A5K6
Rat Swiss Prot No:G3V893
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:ZN335 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):147kD
Background:zinc finger protein 335(ZNF335) Homo sapiens The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure. [provided by RefSeq, Jul 2008],
Function:function:May regulate transcriptional activation through NCOA6.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 13 C2H2-type zinc fingers.,subunit:Interacts with NCOA6, but not with ligand-bound nuclear hormone receptors, including ESR1, THRA, RARA, RXRA, GCCR and PPARA.,tissue specificity:Relatively high expression in the skeletal muscle, thymus, placenta and blood. Moderate expression in the colon, kidney and lung. Low expression in the small intestine, heart, liver and brain.,
Subcellular Location:Nucleus .
Expression:Ubiquitously expressed.