Target：ZN238

Gene Name：ZNF238 RP58 TAZ1 ZBTB18

Protein Name：Zinc finger protein 238 (58 kDa repressor protein) (Transcriptional repressor RP58) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger and BTB domain-containing protein 18) (Zinc finger

Human Gene Id：10472

Human Swiss Prot No：Q99592

Mouse Swiss Prot No：Q9WUK6

Rat Swiss Prot No：Q9JKY3

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：ZN238 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：57kD

Background： This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of chromatin to target genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Function：function:Sequence-specific DNA-binding protein with transcriptional repression activity. Binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. May play a role in the organization of chromosomes in the nucleus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associates with condensed chromatin.,subunit:Interacts with DNMT3A.,tissue specificity:Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.,

Subcellular Location：Nucleus. Associates with condensed chromatin.

Expression：Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.