Target：ZFYVE19

Gene Name：ZFYVE19

Protein Name：Zinc finger FYVE domain-containing protein 19

Human Gene Id：84936

Human Swiss Prot No：Q96K21

Mouse Swiss Prot No：Q9DAZ9

Immunogen：The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360

Specificity：ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZFYVE19;MPFYVE;Zinc finger FYVE domain-containing protein 19;MLL partner containing FYVE domain

Observed Band(KD)：50kD

Background：disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,

Function：disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,

Subcellular Location：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. .

Expression：Detected in brain, heart, skeletal muscle, kidney and liver.