Target:TAF I p48
Gene Name:TAF1A
Protein Name:TATA box-binding protein-associated factor RNA polymerase I subunit A
Human Gene Id:9015
Human Swiss Prot No:Q15573
Mouse Swiss Prot No:P97357
Rat Gene Id:360893
Rat Swiss Prot No:Q3B7U2
Immunogen:The antiserum was produced against synthesized peptide derived from human TAF1A. AA range:301-350
Specificity:TAF I p48 Polyclonal Antibody detects endogenous levels of TAF I p48 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TAF1A;TATA box-binding protein-associated factor RNA polymerase I subunit A;RNA polymerase I-specific TBP-associated factor 48 kDa;TAFI48;TATA box-binding protein-associated factor 1A;TBP-associated factor 1A;Transcription factor SL1;
Observed Band(KD):53kD
Background: This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011],
Function:function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1B and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes.,
Subcellular Location:Nucleus.
Expression: Embryo,Skin,