Target:3MG
Fields:Base excision repair
Gene Name:MPG AAG ANPG MID1
Protein Name:DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)
Human Gene Id:4350
Human Swiss Prot No:P29372
Mouse Swiss Prot No:Q04841
Rat Swiss Prot No:P23571
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:3MG Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):32kD
Background:alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
Function:alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
Subcellular Location:Cytoplasm . Mitochondrion matrix, mitochondrion nucleoid . Nucleus .
Expression: Epithelium,Liver,Pancreas,