Target:IL-20Rβ
Fields:Cytokine-cytokine receptor interaction;Viral protein interaction with cytokine and cytokine receptor;JAK-STAT signaling pathway
Gene Name:IL20RB
Protein Name:Interleukin-20 receptor subunit beta
Human Gene Id:53833
Human Swiss Prot No:Q6UXL0
Immunogen:The antiserum was produced against synthesized peptide derived from human IL20RB. AA range:141-190
Specificity:IL-20Rβ Polyclonal Antibody detects endogenous levels of IL-20Rβ protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:IL20RB;DIRS1;Interleukin-20 receptor subunit beta;IL-20 receptor subunit beta;IL-20R-beta;IL-20RB;IL-20R2
Observed Band(KD):35kD
Background: IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009],
Function:function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RA and heterodimer with IL22RA1.,tissue specificity:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.,
Subcellular Location:Membrane ; Single-pass type I membrane protein .
Expression:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.