Target:CCDC109A
Fields:Calcium signaling pathway;Cellular senescence;NOD-like receptor signaling pathway;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Spinocerebellar ataxia;Prion disease;Pathways of neurodegeneration - multiple diseases
Gene Name:MCU
Protein Name:Calcium uniporter protein mitochondrial
Human Gene Id:90550
Human Swiss Prot No:Q8NE86
Mouse Gene Id:215999
Mouse Swiss Prot No:Q3UMR5
Immunogen:Synthesized peptide derived from the Internal region of human CCDC109A.
Specificity:CCDC109A Polyclonal Antibody detects endogenous levels of CCDC109A protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MCU;C10orf42;CCDC109A;Calcium uniporter protein; mitochondrial;Coiled-coil domain-containing protein 109A
Molecular Weight(Da):40kD
Background: This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
Function:similarity:Belongs to the CCDC109 family.,
Subcellular Location:Mitochondrion inner membrane ; Multi-pass membrane protein .
Expression: Eye,Testis,