Target:ALS2CR4
Gene Name:TMEM237
Protein Name:Transmembrane protein 237
Human Gene Id:65062
Human Swiss Prot No:Q96Q45
Mouse Gene Id:381259
Mouse Swiss Prot No:Q3V0J1
Immunogen:The antiserum was produced against synthesized peptide derived from human ALS2CR4. AA range:181-230
Specificity:ALS2CR4 Polyclonal Antibody detects endogenous levels of ALS2CR4 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TMEM237;ALS2CR4;Transmembrane protein 237;Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
Observed Band(KD):48kD
Background: The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
Subcellular Location:Membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
Expression: Brain,Fetal skin,Ovary,