Target:SYT8
Gene Name:SYT8
Protein Name:Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)
Human Gene Id:90019
Human Swiss Prot No:Q8NBV8
Mouse Swiss Prot No:Q9R0N6
Rat Swiss Prot No:Q925B4
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:SYT8 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):44kD
Background: This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Function:function:Not known. As it is truncated compared to orthologs, its function is not obvious.,sequence caution:The sequence differs from that shown because it is a pre-mRNA.,similarity:Belongs to the synaptotagmin family.,
Subcellular Location:Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .
Expression: Lung,Placenta,Testis,