Target：SWAP

Gene Name：SFSWAP

Protein Name：Splicing factor suppressor of white-apricot homolog

Human Gene Id：6433

Human Swiss Prot No：Q12872

Mouse Swiss Prot No：Q3USH5

Immunogen：The antiserum was produced against synthesized peptide derived from human SFRS8. AA range:201-250

Specificity：SWAP Polyclonal Antibody detects endogenous levels of SWAP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SFSWAP;SFRS8;SWAP;Splicing factor; suppressor of white-apricot homolog;Splicing factor, arginine/serine-rich 8;Suppressor of white apricot protein homolog

Observed Band(KD)：105kD

Background： This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],

Function：function:May function as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 SURP motif repeats.,

Subcellular Location：Nucleus .

Expression： Brain,Epithelium,Eye,Placenta,Skin,