Target：ID1

Fields：Rap1 signaling pathway;TGF-beta signaling pathway;Hippo signaling pathway;Signaling pathways regulating pluripotency of stem cells

Gene Name：ID1 BHLHB24 ID

Protein Name：DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1)

Human Gene Id：3397

Human Swiss Prot No：P41134

Mouse Swiss Prot No：P20067

Rat Swiss Prot No：P41135

Immunogen：Synthesized peptide derived from human protein . at AA range: 30-110

Specificity：ID1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：17kD

Background： The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Function：alternative products:Additional isoforms seem to exist,developmental stage:Expression correlates with proliferation in some types of cells.,function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Heterodimer with other HLH proteins. Interacts with COPS5.,

Subcellular Location：Cytoplasm . Nucleus.

Expression： Lung,Ovary,Placenta,Skin,