Target：AQP8

Fields：Bile secretion

Gene Name：AQP8

Protein Name：Aquaporin-8 (AQP-8)

Human Gene Id：343

Human Swiss Prot No：O94778

Mouse Swiss Prot No：P56404

Rat Swiss Prot No：P56405

Immunogen：Synthesized peptide derived from human protein . at AA range: 70-150

Specificity：AQP8 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：28kD

Background： Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008],

Function：domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon.,

Subcellular Location：Mitochondrion membrane ; Multi-pass membrane protein .

Expression：Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon.