Target：HXK III
Fields：Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Metabolic pathways;Carbon metabolism;Biosynthesis of nucleotide sugars;HIF-1 signaling pathway;Insulin signaling pathway;Type II diabetes mellitus;Carbohydrate digestion and absorption;Shigellosis;Central carbon metabolism in cancer
Gene Name：HK3
Protein Name：Hexokinase-3
Human Gene Id：3101
Human Swiss Prot No：P52790
Mouse Swiss Prot No：Q3TRM8
Immunogen：The antiserum was produced against synthesized peptide derived from human Hexokinase-3. AA range:811-860
Specificity：HXK III Polyclonal Antibody detects endogenous levels of HXK III protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：HK3;Hexokinase-3;Hexokinase type III;HK III
Observed Band(KD)：99kD
Background： Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009],
Function：catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,similarity:Belongs to the hexokinase family.,subunit:Monomer.,
Subcellular Location：cell,mitochondrion,cytosol,
Expression： Blood,Liver,Spleen,
