Target：HXB1

Fields：Signaling pathways regulating pluripotency of stem cells

Gene Name：HOXB1 HOX2I

Protein Name：Homeobox protein Hox-B1 (Homeobox protein Hox-2I)

Human Gene Id：3211

Human Swiss Prot No：P14653

Mouse Swiss Prot No：P17919

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：HXB1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：33kD

Background： This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008],

Function：function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.,polymorphism:The two common alleles; HOX1B*A and HOX1B*B have a frequency of 78.8% and 21.2% respectively.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,

Subcellular Location：Nucleus.

Expression： PCR rescued clones,