Target：HUS1B

Gene Name：HUS1B

Protein Name：Checkpoint protein HUS1B (hHUS1B)

Human Gene Id：135458

Human Swiss Prot No：Q8NHY5

Mouse Swiss Prot No：Q8K572

Immunogen：Synthesized peptide derived from human protein . at AA range: 160-240

Specificity：HUS1B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：30kD

Background： The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the HUS1 family.,subunit:Interacts with RAD1 and RAD9B.,tissue specificity:Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.,

Subcellular Location：nucleolus,checkpoint clamp complex,site of double-strand break,

Expression：Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.