Target：HSPBAP1

Gene Name：HSPBAP1

Protein Name：HSPB1-associated protein 1

Human Gene Id：79663

Human Swiss Prot No：Q96EW2

Mouse Swiss Prot No：Q8BK58

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370

Specificity：HSPBAP1 Polyclonal Antibody detects endogenous levels of HSPBAP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HSPBAP1;PASS1;HSPB1-associated protein 1;27 kDa heat shock protein-associated protein 1;Protein associated with small stress protein 1

Observed Band(KD)：55kD

Background： This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011],

Function：disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed.,

Subcellular Location：Cytoplasm .

Expression：Widely expressed.