Target：HSP77/76

Gene Name：HSPA6/HSPA7

Protein Name：Heat shock 70 kDa protein 6/Putative heat shock 70 kDa protein 7

Human Gene Id：3310

Human Swiss Prot No：P48741

Immunogen：Synthesized peptide derived from the Internal region of human HSP77/76.

Specificity：HSP77/76 Polyclonal Antibody detects endogenous levels of HSP77/76 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HSPA7;HSP70B;Putative heat shock 70 kDa protein 7;Heat shock 70 kDa protein B;HSPA6;HSP70B';Heat shock 70 kDa protein 6;Heat shock 70 kDa protein B'

Observed Band(KD)：40kD

Background：caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,

Function：caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,

Subcellular Location：COP9 signalosome,extracellular exosome,blood microparticle,

Expression： Cerebellum,Lung,Ovary,Skin,