Target：HSP10

Gene Name：HSPE1

Protein Name：10 kDa heat shock protein mitochondrial

Human Gene Id：3336

Human Swiss Prot No：P61604

Mouse Gene Id：15528

Mouse Swiss Prot No：Q64433

Rat Swiss Prot No：P26772

Immunogen：The antiserum was produced against synthesized peptide derived from human HSP10. AA range:51-100

Specificity：HSP10 Polyclonal Antibody detects endogenous levels of HSP10 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HSPE1;10 kDa heat shock protein; mitochondrial;Hsp10;10 kDa chaperonin;Chaperonin 10;CPN10;Early-pregnancy factor;EPF

Observed Band(KD)：10kD

Background： This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011],

Function：function:Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.,induction:By stress.,mass spectrometry: PubMed:7912672,similarity:Belongs to the groES chaperonin family.,subunit:Homohexamer.,

Subcellular Location：Mitochondrion matrix.

Expression： B-cell lymphoma,Uterus,